The 5-Carboxylcytosine (5-caC) (D7S8U) Rabbit mAb Antibody from Cell Signaling Technology is a Rabbit Monoclonal antibody. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, Amoeba/Protozoa, Bacteria/Archaea, Bovine, C. elegans/Worm, Canine, Chicken/Bird, Donkey, Drosophila/Arthropod, Feline, Goat, Guinea Pig, Hamster, Horse, Mollusc, Non-Human Primate, Plant, Porcine, Reptile, Rabbit, Sheep, Virus, Xenopus/Amphibian, Yeast/Fungi, Zebrafish/Fish, Other Invertebrate, and Other Mammalian antigen. The 5-Carboxylcytosine (5-caC) (D7S8U) Rabbit mAb Antibody has been validated for the following applications: Dot Blot, Immunocytochemistry, and Immunofluorescence.
Description
5-Carboxylcytosine (5-caC) (D7S8U) Rabbit mAb detects 5-caC by IF in cells over-expressing the TET1 catalytic domain and by dot blot using double-stranded PCR fragments containing 5-caC. Many cells and tissues contain very low endogenous levels of 5-caC that may fall below the detection limits of this antibody. This antibody has been validated using ELISA, dot blot, and synthetic spike-in DNA MeDIP assays and shows high specificity for 5-caC